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Exosome-functionalized polyetheretherketone-based implant with immunomodulatory property for enhancing osseointegration

The host immune response effecting on biomaterials is critical to determine implant fates and bone regeneration property. Bone marrow stem cells (BMSCs) derived exosomes (Exos) contain multiple biosignal molecules and have been demonstrated to exhibit immunomodulatory functions. Herein, we develop a...

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Detalles Bibliográficos
Autores principales: Fan, Lei, Guan, Pengfei, Xiao, Cairong, Wen, Huiquan, Wang, Qiyou, Liu, Can, Luo, Yian, Ma, Limin, Tan, Guoxin, Yu, Peng, Zhou, Lei, Ning, Chengyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897935/
https://www.ncbi.nlm.nih.gov/pubmed/33665507
http://dx.doi.org/10.1016/j.bioactmat.2021.02.005