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Hepatic Autophagy Deficiency Remodels Gut Microbiota for Adaptive Protection via FGF15-FGFR4 Signaling

BACKGROUND & AIMS: The functions of the liver and the intestine are closely tied in both physiological and pathologic conditions. The gut microbiota (GM) often cause deleterious effects during hepatic pathogenesis. Autophagy is essential for liver homeostasis, but the impact of hepatic autophagy...

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Detalles Bibliográficos
Autores principales: Yan, Shengmin, Khambu, Bilon, Chen, Xiaoyun, Dong, Zheng, Guo, Grace, Yin, Xiao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898036/
https://www.ncbi.nlm.nih.gov/pubmed/33127558
http://dx.doi.org/10.1016/j.jcmgh.2020.10.011