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In vivo Pharmacokinetics and in vitro Release of Imatinib Mesylate-Loaded Liposomes for Pulmonary Delivery

BACKGROUND: Pulmonary arterial hypertension (PAH) is characterized by abnormal proliferation of vascular endothelial and smooth muscle cells and causes occlusion of pulmonary arterioles that eventually results in right heart failure and death. The platelet-derived growth factor (PDGF) plays a promin...

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Detalles Bibliográficos
Autores principales: Xu, Hongfei, Ji, Hongyu, Li, Zerong, Qiao, Wenmei, Wang, Chenghao, Tang, Jingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898055/
https://www.ncbi.nlm.nih.gov/pubmed/33628019
http://dx.doi.org/10.2147/IJN.S294626