Evaluation of bone and kidney toxicity of BT2-peg2, a potential carrier for the targeted delivery of antibiotics to bone

Previous studies have demonstrated that the bone targeting agent BT2-peg2 (BT2-minipeg2, 9), when conjugated to vancomycin and delivered systemically by intravenous (IV) or intraperitoneal (IP) injection accumulates in bone to a greater degree than vancomycin alone, but that this accumulation is ass...

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Detalles Bibliográficos
Autores principales: Albayati, Zaineb A.F., Penthala, Narsimha R., Bommagani, Shobanbabu, Post, Ginell R., Smeltzer, Mark S., Crooks, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898066/
https://www.ncbi.nlm.nih.gov/pubmed/33665133
http://dx.doi.org/10.1016/j.toxrep.2021.02.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898066/
https://www.ncbi.nlm.nih.gov/pubmed/33665133
http://dx.doi.org/10.1016/j.toxrep.2021.02.002

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