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Catalpol Protects Against Spinal Cord Injury in Mice Through Regulating MicroRNA-142-Mediated HMGB1/TLR4/NF-κB Signaling Pathway

Background: Spinal cord injury (SCI) is a devastating condition that leads to paralysis, disability and even death in severe cases. Inflammation, apoptosis and oxidative stress in neurons are key pathogenic processes in SCI. Catalpol (CTP), an iridoid glycoside extracted from Rehmannia glutinosa, ha...

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Detalles Bibliográficos
Autores principales: Xia, Hougang, Wang, Dandan, Guo, Xiaohui, Wu, Kaidi, Huang, Fuwei, Feng, Yanjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898164/
https://www.ncbi.nlm.nih.gov/pubmed/33628189
http://dx.doi.org/10.3389/fphar.2020.630222