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CircHIPK3 Alleviates High Glucose Toxicity to Human Renal Tubular Epithelial HK-2 Cells Through Regulation of miR-326/miR-487a-3p/SIRT1

BACKGROUND: The intervention of circular RNA HIPK3 (circHIPK3) in diabetes has drawn increasing attention in recent years. However, the underlying mechanism of circHIPK3 in diabetic nephropathy (DN) has not been fully elucidated. Thus, the current study aims to investigate the role of circHIPK3 in h...

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Detalles Bibliográficos
Autores principales: Zhuang, Langen, Wang, Ziwei, Hu, Xiaolei, Yang, Qingqing, Pei, Xiaoyan, Jin, Guoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898210/
https://www.ncbi.nlm.nih.gov/pubmed/33628038
http://dx.doi.org/10.2147/DMSO.S289624