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Poor Prognosis of Pulmonary Adenosquamous Carcinoma with NRAS and HRAS Double Mutation

RAS mutations constitute one of the major tumorigenic mechanisms and are detected in approximately 20% of lung cancers. The most frequent mutated and well-studied RAS isoform is KRAS, which is associated with an overall poor prognosis in non-small-cell lung cancer (NSCLC). However, the clinical sign...

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Detalles Bibliográficos
Autores principales: Zhao, Jidong, Zhang, Xiangmei, He, Ming, Chen, Xin, Cui, Xing, Qin, Tian, Niu, Xueliang, Zhao, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898223/
https://www.ncbi.nlm.nih.gov/pubmed/33628034
http://dx.doi.org/10.2147/OTT.S295813