Aβ Oligomers Dysregulate Calcium Homeostasis by Mechanosensitive Activation of AMPA and NMDA Receptors

[Image: see text] Alzheimer’s disease, which is the most common form of dementia, is characterized by the aggregation of the amyloid β peptide (Aβ) and by an impairment of calcium homeostasis caused by excessive activation of glutamatergic receptors (excitotoxicity). Here, we studied the effects on...

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Detalles Bibliográficos
Autores principales: Fani, Giulia, Mannini, Benedetta, Vecchi, Giulia, Cascella, Roberta, Cecchi, Cristina, Dobson, Christopher M., Vendruscolo, Michele, Chiti, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898266/
https://www.ncbi.nlm.nih.gov/pubmed/33538575
http://dx.doi.org/10.1021/acschemneuro.0c00811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898266/
https://www.ncbi.nlm.nih.gov/pubmed/33538575
http://dx.doi.org/10.1021/acschemneuro.0c00811

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