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Dual Site-Specific Chemoenzymatic Antibody Fragment Conjugation Using CRISPR-Based Hybridoma Engineering

[Image: see text] Functionalized antibodies and antibody fragments have found applications in the fields of biomedical imaging, theranostics, and antibody–drug conjugates (ADC). In addition, therapeutic and theranostic approaches benefit from the possibility to deliver more than one type of cargo to...

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Detalles Bibliográficos
Autores principales: Le Gall, Camille M., van der Schoot, Johan M. S., Ramos-Tomillero, Iván, Khalily, Melek Parlak, van Dalen, Floris J., Wijfjes, Zacharias, Smeding, Liyan, van Dalen, Duco, Cammarata, Anna, Bonger, Kimberly M., Figdor, Carl G., Scheeren, Ferenc A., Verdoes, Martijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898269/
https://www.ncbi.nlm.nih.gov/pubmed/33476135
http://dx.doi.org/10.1021/acs.bioconjchem.0c00673