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2′,4′‐BNA/LNA with 9‐(2‐Aminoethoxy)‐1,3‐diaza‐2‐oxophenoxazine Efficiently Forms Duplexes and Has Enhanced Enzymatic Resistance

Artificial nucleic acids are widely used in various technologies, such as nucleic acid therapeutics and DNA nanotechnologies requiring excellent duplex‐forming abilities and enhanced nuclease resistance. 2′‐O,4′‐C‐Methylene‐bridged nucleic acid/locked nucleic acid (2′,4′‐BNA/LNA) with 1,3‐diaza‐2‐ox...

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Detalles Bibliográficos
Autores principales: Kishimoto, Yuki, Nakagawa, Osamu, Fujii, Akane, Yoshioka, Kotaro, Nagata, Tetsuya, Yokota, Takanori, Hari, Yoshiyuki, Obika, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898338/
https://www.ncbi.nlm.nih.gov/pubmed/33280173
http://dx.doi.org/10.1002/chem.202003982