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Energy-dependent protein folding: modeling how a protein folding machine may work

Background: Proteins fold robustly and reproducibly in vivo, but many cannot fold in vitro in isolation from cellular components. Despite the remarkable progress that has been achieved by the artificial intelligence approaches in predicting the protein native conformations, the pathways that lead to...

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Detalles Bibliográficos
Autores principales: Sahakyan, Harutyun, Nazaryan, Karen, Mushegian, Arcady, Sorokina, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898354/
https://www.ncbi.nlm.nih.gov/pubmed/33633838
http://dx.doi.org/10.12688/f1000research.28175.1