The ubiquitin ligase RNF8 regulates Rho GTPases and promotes cytoskeletal changes and motility in triple‐negative breast cancer cells

The ubiquitin ligase RNF8 is known to induce epithelial‐to‐mesenchymal (EMT) transition and metastasis in triple‐negative breast cancer (TNBC). Besides EMT, Rho GTPases have been shown as key regulators in metastasis. In this study, we investigated the role of RNF8 in regulating Rho GTPases and cell...

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Detalles Bibliográficos
Autores principales: Pereira De Carvalho, Bruno, Chern, Yi‐Jye, He, Jiabei, Chan, Chia‐Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898409/
https://www.ncbi.nlm.nih.gov/pubmed/33205415
http://dx.doi.org/10.1002/1873-3468.13999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898409/
https://www.ncbi.nlm.nih.gov/pubmed/33205415
http://dx.doi.org/10.1002/1873-3468.13999

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