Megabase-scale methylation phasing using nanopore long reads and NanoMethPhase

The ability of nanopore sequencing to simultaneously detect modified nucleotides while producing long reads makes it ideal for detecting and phasing allele-specific methylation. However, there is currently no complete software for detecting SNPs, phasing haplotypes, and mapping methylation to these...

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Detalles Bibliográficos
Autores principales: Akbari, Vahid, Garant, Jean-Michel, O’Neill, Kieran, Pandoh, Pawan, Moore, Richard, Marra, Marco A., Hirst, Martin, Jones, Steven J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898412/
https://www.ncbi.nlm.nih.gov/pubmed/33618748
http://dx.doi.org/10.1186/s13059-021-02283-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898412/
https://www.ncbi.nlm.nih.gov/pubmed/33618748
http://dx.doi.org/10.1186/s13059-021-02283-5

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