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Megabase-scale methylation phasing using nanopore long reads and NanoMethPhase
The ability of nanopore sequencing to simultaneously detect modified nucleotides while producing long reads makes it ideal for detecting and phasing allele-specific methylation. However, there is currently no complete software for detecting SNPs, phasing haplotypes, and mapping methylation to these...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898412/ https://www.ncbi.nlm.nih.gov/pubmed/33618748 http://dx.doi.org/10.1186/s13059-021-02283-5 |