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Streptococcus suis serotype 2 enolase interaction with host brain microvascular endothelial cells and RPSA-induced apoptosis lead to loss of BBB integrity

Host proteins interacting with pathogens are receiving more attention as potential therapeutic targets in molecular medicine. Streptococcus suis serotype 2 (SS2) is an important cause of meningitis in both humans and pigs worldwide. SS2 Enolase (Eno) has previously been identified as a virulence fac...

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Detalles Bibliográficos
Autores principales: Liu, Hongtao, Lei, Siyu, Jia, Li, Xia, Xiaojing, Sun, Yingying, Jiang, Hexiang, Zhu, Rining, Li, Shuguang, Qu, Guanggang, Gu, Jingmin, Sun, Changjiang, Feng, Xin, Han, Wenyu, Langford, Paul R., Lei, Liancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898445/
https://www.ncbi.nlm.nih.gov/pubmed/33618766
http://dx.doi.org/10.1186/s13567-020-00887-6