A novel role of DNA polymerase λ in translesion synthesis in conjunction with DNA polymerase ζ

By extending synthesis opposite from a diverse array of DNA lesions, DNA polymerase (Pol) ζ performs a crucial role in translesion synthesis (TLS). In yeast and cancer cells, Rev1 functions as an indispensable scaffolding component of Polζ and it imposes highly error-prone TLS upon Polζ. However, fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoon, Jung-Hoon, Basu, Debashree, Sellamuthu, Karthi, Johnson, Robert E, Prakash, Satya, Prakash, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898466/
https://www.ncbi.nlm.nih.gov/pubmed/33514655
http://dx.doi.org/10.26508/lsa.202000900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898466/
https://www.ncbi.nlm.nih.gov/pubmed/33514655
http://dx.doi.org/10.26508/lsa.202000900

Ejemplares similares