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A novel role of DNA polymerase λ in translesion synthesis in conjunction with DNA polymerase ζ
By extending synthesis opposite from a diverse array of DNA lesions, DNA polymerase (Pol) ζ performs a crucial role in translesion synthesis (TLS). In yeast and cancer cells, Rev1 functions as an indispensable scaffolding component of Polζ and it imposes highly error-prone TLS upon Polζ. However, fo...
Autores principales: | Yoon, Jung-Hoon, Basu, Debashree, Sellamuthu, Karthi, Johnson, Robert E, Prakash, Satya, Prakash, Louise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898466/ https://www.ncbi.nlm.nih.gov/pubmed/33514655 http://dx.doi.org/10.26508/lsa.202000900 |
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