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Hepatitis B Virus–Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carcinoma

BACKGROUND AND AIMS: Hepatitis B virus (HBV) integrations are common in hepatocellular carcinoma (HCC). In particular, alterations of the telomerase reverse transcriptase (TERT) gene by HBV integrations are frequent; however, the molecular mechanism and functional consequence underlying TERT HBV int...

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Detalles Bibliográficos
Autores principales: Sze, Karen Man‐Fong, Ho, Daniel Wai‐Hung, Chiu, Yung‐Tuen, Tsui, Yu‐Man, Chan, Lo‐Kong, Lee, Joyce Man‐Fong, Chok, Kenneth Siu‐Ho, Chan, Albert Chi‐Yan, Tang, Chung‐Ngai, Tang, Victor Wai‐Lun, Lo, Irene Lai‐Oi, Yau, Derek Tsz‐Wai, Cheung, Tan‐To, Ng, Irene Oi‐Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898544/
https://www.ncbi.nlm.nih.gov/pubmed/32170761
http://dx.doi.org/10.1002/hep.31231