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A novel canis lupus familiaris reference genome improves variant resolution for use in breed-specific GWAS

Reference genome fidelity is critically important for genome wide association studies, yet most vary widely from the study population. A typical whole genome sequencing approach implies short-read technologies resulting in fragmented assemblies with regions of ambiguity. Further information is lost...

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Detalles Bibliográficos
Autores principales: Player, Robert A, Forsyth, Ellen R, Verratti, Kathleen J, Mohr, David W, Scott, Alan F, Bradburne, Christopher E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898556/
https://www.ncbi.nlm.nih.gov/pubmed/33514656
http://dx.doi.org/10.26508/lsa.202000902