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Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family
The human glucose transporters GLUT1 and GLUT3 have a central role in glucose uptake as canonical members of the Sugar Porter (SP) family. GLUT1 and GLUT3 share a fully conserved substrate-binding site with identical substrate coordination, but differ significantly in transport affinity in line with...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898563/ https://www.ncbi.nlm.nih.gov/pubmed/33536238 http://dx.doi.org/10.26508/lsa.202000858 |