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Classification of intestinal T‐cell receptor repertoires using machine learning methods can identify patients with coeliac disease regardless of dietary gluten status

In coeliac disease (CeD), immune‐mediated small intestinal damage is precipitated by gluten, leading to variable symptoms and complications, occasionally including aggressive T‐cell lymphoma. Diagnosis, based primarily on histopathological examination of duodenal biopsies, is confounded by poor conc...

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Detalles Bibliográficos
Autores principales: Foers, Andrew D, Shoukat, M Saad, Welsh, Oliver E, Donovan, Killian, Petry, Russell, Evans, Shelley C, FitzPatrick, Michael EB, Collins, Nadine, Klenerman, Paul, Fowler, Anna, Soilleux, Elizabeth J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898595/
https://www.ncbi.nlm.nih.gov/pubmed/33225446
http://dx.doi.org/10.1002/path.5592