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ER targeting of non-imported mitochondrial carrier proteins is dependent on the GET pathway

Deficiencies in mitochondrial import cause the toxic accumulation of non-imported mitochondrial precursor proteins. Numerous fates for non-imported mitochondrial precursors have been identified in budding yeast, including proteasomal destruction, deposition into protein aggregates, and mistargeting...

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Detalles Bibliográficos
Autores principales: Xiao, Tianyao, Shakya, Viplendra PS, Hughes, Adam L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898604/
https://www.ncbi.nlm.nih.gov/pubmed/33479049
http://dx.doi.org/10.26508/lsa.202000918