Genetic ablation of FASN attenuates the invasive potential of prostate cancer driven by Pten loss

Loss of the tumor suppressor gene Pten in murine prostate recapitulates human carcinogenesis and causes stromal proliferation surrounding murine prostate intraepithelial neoplasia (mPIN), which is reactive to microinvasion. In turn, invasion has been shown to be regulated in part by de novo fatty ac...

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Detalles Bibliográficos
Autores principales: Bastos, Débora C, Ribeiro, Caroline F, Ahearn, Thomas, Nascimento, Jéssica, Pakula, Hubert, Clohessy, John, Mucci, Lorelei, Roberts, Thomas, Zanata, Silvio M, Zadra, Giorgia, Loda, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898611/
https://www.ncbi.nlm.nih.gov/pubmed/33166087
http://dx.doi.org/10.1002/path.5587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898611/
https://www.ncbi.nlm.nih.gov/pubmed/33166087
http://dx.doi.org/10.1002/path.5587

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