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1,6-hexanediol rapidly immobilizes and condenses chromatin in living human cells

Liquid droplets formed inside the cell by liquid–liquid phase separation maintain membrane-less condensates/bodies (or compartments). These droplets are important for concentrating certain molecules and facilitating spatiotemporal regulation of cellular functions. 1,6-hexanediol (1,6-HD), an aliphat...

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Detalles Bibliográficos
Autores principales: Itoh, Yuji, Iida, Shiori, Tamura, Sachiko, Nagashima, Ryosuke, Shiraki, Kentaro, Goto, Tatsuhiko, Hibino, Kayo, Ide, Satoru, Maeshima, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898662/
https://www.ncbi.nlm.nih.gov/pubmed/33536240
http://dx.doi.org/10.26508/lsa.202001005