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Prebiotically Plausible RNA Activation Compatible with Ribozyme‐Catalyzed Ligation

RNA‐catalyzed RNA ligation is widely believed to be a key reaction for primordial biology. However, since typical chemical routes towards activating RNA substrates are incompatible with ribozyme catalysis, it remains unclear how prebiotic systems generated and sustained pools of activated building b...

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Detalles Bibliográficos
Autores principales: Song, Emilie Yeonwha, Jiménez, Eddy Ivanhoe, Lin, Huacan, Le Vay, Kristian, Krishnamurthy, Ramanarayanan, Mutschler, Hannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898671/
https://www.ncbi.nlm.nih.gov/pubmed/33128282
http://dx.doi.org/10.1002/anie.202010918