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IRBIT activates NBCe1‐B by releasing the auto‐inhibition module from the transmembrane domain
KEY POINTS: The electrogenic Na(+)/HCO(3) (−)cotransporter NBCe1‐B is widely expressed in many tissues, including pancreas, submandibular gland, brain, heart, etc. NBCe1‐B has very low activity under basal condition due to auto‐inhibition, but can be fully activated by protein interaction with the I...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898672/ https://www.ncbi.nlm.nih.gov/pubmed/33237573 http://dx.doi.org/10.1113/JP280578 |