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IRBIT activates NBCe1‐B by releasing the auto‐inhibition module from the transmembrane domain

KEY POINTS: The electrogenic Na(+)/HCO(3) (−)cotransporter NBCe1‐B is widely expressed in many tissues, including pancreas, submandibular gland, brain, heart, etc. NBCe1‐B has very low activity under basal condition due to auto‐inhibition, but can be fully activated by protein interaction with the I...

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Detalles Bibliográficos
Autores principales:	Su, Pan, Wu, Han, Wang, Meng, Cai, Lu, Liu, Ying, Chen, Li‐Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Molecular and Cellular
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898672/ https://www.ncbi.nlm.nih.gov/pubmed/33237573 http://dx.doi.org/10.1113/JP280578

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