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PKCε stimulation of TRPV1 orchestrates carotid body responses to asthmakines

KEY POINTS: We have previously shown that carotid body stimulation by lysophosphatidic acid elicits a reflex stimulation of vagal efferent activity sufficient to cause bronchoconstriction in asthmatic rats. Here, we show that pathophysiological concentrations of asthma‐associated prototypical Th2 cy...

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Detalles Bibliográficos
Autores principales: Jendzjowsky, Nicholas G., Roy, Arijit, Iftinca, Mircea, Barioni, Nicole O., Kelly, Margaret M., Herrington, Brittney A., Visser, Frank, Altier, Christophe, Wilson, Richard J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898719/
https://www.ncbi.nlm.nih.gov/pubmed/33180962
http://dx.doi.org/10.1113/JP280749