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A prefrontal–paraventricular thalamus circuit requires juvenile social experience to regulate adult sociability in mice

Juvenile social isolation reduces sociability in adulthood, but the neural circuit mechanisms are poorly understood. We found that, in male mice, 2 weeks of social isolation immediately following weaning leads to a failure to activate medial prefrontal cortex (mPFC) neurons projecting to the posteri...

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Detalles Bibliográficos
Autores principales: Yamamuro, Kazuhiko, Bicks, Lucy K., Leventhal, Michael B., Kato, Daisuke, Im, Susanna, Flanigan, Meghan E., Garkun, Yury, Norman, Kevin J., Caro, Keaven, Sadahiro, Masato, Kullander, Klas, Akbarian, Schahram, Russo, Scott J., Morishita, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898783/
https://www.ncbi.nlm.nih.gov/pubmed/32868932
http://dx.doi.org/10.1038/s41593-020-0695-6