RNA‐PROTACs: Degraders of RNA‐Binding Proteins

Defects in the functions of RNA binding proteins (RBPs) are at the origin of many diseases; however, targeting RBPs with conventional drugs has proven difficult. PROTACs are a new class of drugs that mediate selective degradation of a target protein through a cell's ubiquitination machinery. PR...

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Detalles Bibliográficos
Autores principales: Ghidini, Alice, Cléry, Antoine, Halloy, François, Allain, Frédéric H. T., Hall, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898822/
https://www.ncbi.nlm.nih.gov/pubmed/33108679
http://dx.doi.org/10.1002/anie.202012330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898822/
https://www.ncbi.nlm.nih.gov/pubmed/33108679
http://dx.doi.org/10.1002/anie.202012330

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