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SNPs associated with colorectal cancer at 15q13.3 affect risk enhancers that modulate GREM1 gene expression

Several genome wide association studies of colorectal cancer (CRC) have identified single nucleotide polymorphisms (SNPs) on chromosome 15q13.3 associated with CRC risk. To identify functional variant(s) underlying this association, we investigated SNPs in linkage disequilibrium with the risk‐associ...

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Detalles Bibliográficos
Autores principales: Fortini, Barbara K., Tring, Stephanie, Devall, Matthew A., Ali, Mourad Wagdy, Plummer, Sarah J., Casey, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898835/
https://www.ncbi.nlm.nih.gov/pubmed/33476087
http://dx.doi.org/10.1002/humu.24166