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Tag‐Free Internal RNA Labeling and Photocaging Based on mRNA Methyltransferases
The mRNA modification N(6)‐methyladenosine (m(6)A) is associated with multiple roles in cell function and disease. The methyltransferases METTL3‐METTL14 and METTL16 act as “writers” for different target transcripts and sequence motifs. The modification is perceived by dedicated “reader” and “eraser”...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898847/ https://www.ncbi.nlm.nih.gov/pubmed/33095964 http://dx.doi.org/10.1002/anie.202013936 |