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E2F7 Is a Potent Inhibitor of Liver Tumor Growth in Adult Mice

BACKGROUND AND AIMS: Up‐regulation of the E2F‐dependent transcriptional network has been identified in nearly every human malignancy and is an important driver of tumorigenesis. Two members of the E2F family, E2F7 and E2F8, are potent repressors of E2F‐dependent transcription. They are atypical in t...

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Detalles Bibliográficos
Autores principales: Moreno, Eva, Toussaint, Mathilda J.M., van Essen, Saskia C., Bongiovanni, Laura, van Liere, Elsbeth A., Koster, Mirjam H., Yuan, Ruixue, van Deursen, Jan M., Westendorp, Bart, de Bruin, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898887/
https://www.ncbi.nlm.nih.gov/pubmed/32259305
http://dx.doi.org/10.1002/hep.31259