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Sperm proteins and cancer‐testis antigens are released by the seminiferous tubules in mice and men

Sperm develop from puberty in the seminiferous tubules, inside the blood‐testis barrier to prevent their recognition as “non‐self” by the immune system, and it is widely assumed that human sperm‐specific proteins cannot access the circulatory or immune systems. Sperm‐specific proteins aberrantly exp...

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Detalles Bibliográficos
Autores principales: O'Donnell, Liza, Rebourcet, Diane, Dagley, Laura F., Sgaier, Raouda, Infusini, Giuseppe, O'Shaughnessy, Peter J., Chalmel, Frederic, Fietz, Daniela, Weidner, Wolfgang, Legrand, Julien M. D., Hobbs, Robin M., McLachlan, Robert I., Webb, Andrew I., Pilatz, Adrian, Diemer, Thorsten, Smith, Lee B., Stanton, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898903/
https://www.ncbi.nlm.nih.gov/pubmed/33565176
http://dx.doi.org/10.1096/fj.202002484R