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Depletion of MHC supertype during domestication can compromise immunocompetence

The major histocompatibility complex (MHC) plays an important role in infectious disease resistance. The presence of certain MHC alleles and functionally similar groups of MHC alleles (i.e., supertypes) has been associated with resistance to particular parasite species. Farmed and domesticated fish...

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Detalles Bibliográficos
Autores principales: Smallbone, Willow, Ellison, Amy, Poulton, Simon, van Oosterhout, Cock, Cable, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898906/
https://www.ncbi.nlm.nih.gov/pubmed/33274493
http://dx.doi.org/10.1111/mec.15763