Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular calcification

AIMS: Vascular calcification is a recognized predictor of cardiovascular risk in the diabetic patient, with DNA damage and accelerated senescence linked to oxidative stress-associated pathological calcification. Having previously shown that systemic SIRT1 is reduced in diabetes, the aim was to estab...

Descripción completa

Detalles Bibliográficos
Autores principales: Bartoli-Leonard, Francesca, Wilkinson, Fiona L, Schiro, Andrew, Serracino Inglott, Ferdinand, Alexander, M Yvonne, Weston, Ria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898956/
https://www.ncbi.nlm.nih.gov/pubmed/32402066
http://dx.doi.org/10.1093/cvr/cvaa134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898956/
https://www.ncbi.nlm.nih.gov/pubmed/32402066
http://dx.doi.org/10.1093/cvr/cvaa134

Ejemplares similares