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Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular calcification
AIMS: Vascular calcification is a recognized predictor of cardiovascular risk in the diabetic patient, with DNA damage and accelerated senescence linked to oxidative stress-associated pathological calcification. Having previously shown that systemic SIRT1 is reduced in diabetes, the aim was to estab...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898956/ https://www.ncbi.nlm.nih.gov/pubmed/32402066 http://dx.doi.org/10.1093/cvr/cvaa134 |