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Identification of an amino-terminus determinant critical for ryanodine receptor/Ca(2+) release channel function

AIMS : The cardiac ryanodine receptor (RyR2), which mediates intracellular Ca(2+) release to trigger cardiomyocyte contraction, participates in development of acquired and inherited arrhythmogenic cardiac disease. This study was undertaken to characterize the network of inter- and intra-subunit inte...

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Detalles Bibliográficos
Autores principales: Seidel, Monika, de Meritens, Camille Rabesahala, Johnson, Louisa, Parthimos, Dimitris, Bannister, Mark, Thomas, Nia Lowri, Ozekhome-Mike, Esizaze, Lai, Francis Anthony, Zissimopoulos, Spyros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898959/
https://www.ncbi.nlm.nih.gov/pubmed/32077934
http://dx.doi.org/10.1093/cvr/cvaa043