Autophagosome maturation stymied by SARS-CoV-2

Many pathogens are capable of disrupting autophagy within host cells. In this issue of Developmental Cell, Miao et al. discover that the SARS-CoV-2 protein ORF3a inhibits autophagosome-lysosome fusion by dysregulating the HOPS complex.

Detalles Bibliográficos
Autores principales: Yim, Willa Wen-You, Mizushima, Noboru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898975/
https://www.ncbi.nlm.nih.gov/pubmed/33621488
http://dx.doi.org/10.1016/j.devcel.2021.02.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898975/
https://www.ncbi.nlm.nih.gov/pubmed/33621488
http://dx.doi.org/10.1016/j.devcel.2021.02.002

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