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Autophagosome maturation stymied by SARS-CoV-2
Many pathogens are capable of disrupting autophagy within host cells. In this issue of Developmental Cell, Miao et al. discover that the SARS-CoV-2 protein ORF3a inhibits autophagosome-lysosome fusion by dysregulating the HOPS complex.
Autores principales: | Yim, Willa Wen-You, Mizushima, Noboru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898975/ https://www.ncbi.nlm.nih.gov/pubmed/33621488 http://dx.doi.org/10.1016/j.devcel.2021.02.002 |
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