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Three-dimensional interactions between enhancers and promoters during intestinal differentiation depend upon HNF4

Cells in renewing tissues exhibit dramatic transcriptional changes as they differentiate. The contribution of chromatin looping to tissue renewal is incompletely understood. Enhancer-promoter interactions could be relatively stable as cells transition from progenitor to differentiated states; altern...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Cao, Weihuan, Aita, Rohit, Aldea, Dennis, Flores, Juan, Gao, Nan, Bonder, Edward M., Ellison, Christopher E., Verzi, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899294/
https://www.ncbi.nlm.nih.gov/pubmed/33503426
http://dx.doi.org/10.1016/j.celrep.2020.108679