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Magnetic ligand fishing using immobilized DPP-IV for identification of antidiabetic ligands in lingonberry extract

In this work, a new magnetic ligand fishing probe for discovery of DPP-IV inhibitory ligands was developed and it was tested as a proof of concept on the fruit extract of Vaccinium vitis-idaea (lingonberry). The ligands were shown to have appreciable dipeptidyl peptidase IV (DPP-IV) inhibitory activ...

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Detalles Bibliográficos
Autores principales: Lima, Rita de Cássia Lemos, Böcker, Ulrike, McDougall, Gordon J., Allwood, J. William, Afseth, Nils Kristian, Wubshet, Sileshi Gizachew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899330/
https://www.ncbi.nlm.nih.gov/pubmed/33617581
http://dx.doi.org/10.1371/journal.pone.0247329