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Establishment of an in vitro culture system to study the developmental biology of Onchocerca volvulus with implications for anti-Onchocerca drug discovery and screening

BACKGROUND: Infections with Onchocerca volvulus nematodes remain a threat in Sub-Saharan Africa after three decades of ivermectin mass drug administration. Despite this effort, there is still an urgent need for understanding the parasite biology especially the mating behaviour and nodule formation a...

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Detalles Bibliográficos
Autores principales: Gandjui, Narcisse V. T., Njouendou, Abdel J., Gemeg, Eric N., Fombad, Fanny F., Ritter, Manuel, Kien, Chi A., Chunda, Valerine C., Fru, Jerome, Esum, Mathias E., Hübner, Marc P., Enyong, Peter A., Hoerauf, Achim, Wanji, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899360/
https://www.ncbi.nlm.nih.gov/pubmed/33561123
http://dx.doi.org/10.1371/journal.pntd.0008513