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Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination

Recently approved vaccines have already shown remarkable protection in limiting SARS-CoV-2 associated disease. However, immunologic mechanism(s) of protection, as well as how boosting alters immunity to wildtype and newly emerging strains, remain incompletely understood. Here we deeply profiled the...

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Detalles Bibliográficos
Autores principales: Alter, Galit, Gorman, Matthew, Patel, Nita, Guebre-Xabier, Mimi, Zhu, Alex, Atyeo, Caroline, Pullen, Krista, Loos, Carolin, Goez-Gazi, Yenny, Carrion, Ricardo, Tian, Jing-Hui, Yuan, Dansu, Bowman, Kathryn, Zhou, Bin, Maciejewski, Sonia, McGrath, Marisa, Logue, James, Frieman, Matthew, Montefiori, David, Schendel, Sharon, Saphire, Erica Ollmann, Lauffenburger, Douglas, Greene, Ann, Portnoff, Alyse, Massare, Michael, Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Mann, Colin, Amanat, Fatima, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899467/
https://www.ncbi.nlm.nih.gov/pubmed/33619473
http://dx.doi.org/10.21203/rs.3.rs-200342/v1