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Extrahepatic cytochrome P450 epoxygenases: pathophysiology and clinical significance in human gastrointestinal cancers

Cytochrome P450 (CYP) epoxygenases, a multi-gene superfamily of heme-containing enzymes, are commonly known to metabolize endogenous arachidonic acid (AA) to epoxyeicosatrienoic acids (EETs). The role of CYPs is mostly studied in liver drugs metabolism, cardiac pathophysiology, and hypertension fiel...

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Detalles Bibliográficos
Autores principales: Pidkovka, Nataliya, Rachkevych, Olena, Belkhiri, Abbes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899545/
https://www.ncbi.nlm.nih.gov/pubmed/33659048
http://dx.doi.org/10.18632/oncotarget.27893