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Low concentrations of vorinostat decrease EB1 expression in GBM cells and affect microtubule dynamics, cell survival and migration

Glioblastoma multiform (GBM) is the most frequent primitive brain tumor with a high recurrence and mortality. Histone deacetylase inhibitors (HDACi) have evoked great interest because they are able to change transcriptomic profiles to promote tumor cell death but also induce side effects due to the...

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Detalles Bibliográficos
Autores principales: Perez, Thomas, Bergès, Raphaël, Maccario, Hélène, Oddoux, Sarah, Honoré, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899546/
https://www.ncbi.nlm.nih.gov/pubmed/33659042
http://dx.doi.org/10.18632/oncotarget.27892