Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer

Reg4 is highly expressed in gastrointestinal malignancies and acts as a mitogenic and pro-invasive factor. Our recent works suggest that Reg4 binds with CD44 and induces its proteolytic cleavage to release intra-cytoplasmic domain of CD44 (CD44ICD). The goal of this study is to demonstrate clinical...

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Detalles Bibliográficos
Autores principales: Sninsky, Jared A., Bishnupuri, Kumar S., González, Iván, Trikalinos, Nikolaos A., Chen, Ling, Dieckgraefe, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899555/
https://www.ncbi.nlm.nih.gov/pubmed/33659040
http://dx.doi.org/10.18632/oncotarget.27896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899555/
https://www.ncbi.nlm.nih.gov/pubmed/33659040
http://dx.doi.org/10.18632/oncotarget.27896

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