Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives

A small library of coumarin and their psoralen analogues EMAC10157a-b-d-g and EMAC10160a-b-d-g has been designed and synthesised to investigate the effect of structural modifications on their inhibition ability and selectivity profile towards carbonic anhydrase isoforms I, II, IX, and XII. None of t...

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Detalles Bibliográficos
Autores principales: Meleddu, Rita, Deplano, Serenella, Maccioni, Elias, Ortuso, Francesco, Cottiglia, Filippo, Secci, Daniela, Onali, Alessia, Sanna, Erica, Angeli, Andrea, Angius, Rossella, Alcaro, Stefano, Supuran, Claudiu T., Distinto, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899656/
https://www.ncbi.nlm.nih.gov/pubmed/33602041
http://dx.doi.org/10.1080/14756366.2021.1887171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899656/
https://www.ncbi.nlm.nih.gov/pubmed/33602041
http://dx.doi.org/10.1080/14756366.2021.1887171

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