Skin-specific knockdown of hyaluronan in mice by an optimized topical 4-methylumbelliferone formulation

Hyaluronan (HA) is abundant in the skin; while HA can be synthesized by the synthases (HAS1-3), HAS2 is the leading contributor. Dysregulation and accumulation of HA is implicated in the pathogenesis of diseases such as keloid scarring, lymphedema and metastatic melanoma. To understand how HA synthe...

Descripción completa

Detalles Bibliográficos
Autores principales: Steen, Emily H., Short, Walker D., Li, Hui, Parikh, Umang M., Blum, Alexander, Templeman, Natalie, Nagy, Nadine, Bollyky, Paul L., Keswani, Sundeep G., Balaji, Swathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899664/
https://www.ncbi.nlm.nih.gov/pubmed/33605181
http://dx.doi.org/10.1080/10717544.2021.1886376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899664/
https://www.ncbi.nlm.nih.gov/pubmed/33605181
http://dx.doi.org/10.1080/10717544.2021.1886376

Ejemplares similares