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Coming together at the hinges: Therapeutic prospects of IgG3
The human IgG3 subclass is conspicuously absent among the formats for approved monoclonal antibody therapies and Fc fusion protein biologics. Concern about the potential for rapid degradation, reduced plasma half-life, and increased immunogenicity due to marked variation in allotypes has apparently...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899677/ https://www.ncbi.nlm.nih.gov/pubmed/33602056 http://dx.doi.org/10.1080/19420862.2021.1882028 |